Knome Selected as Technology Partner by Johns Hopkins for Landmark 1,000 Genomes Asthma Research
Knome’s informatics and software tools to be used to interpret whole genomes of African American and African Caribbean asthma patients
CAMBRIDGE, MA – January 9, 2012 – Knome, Inc., the human genome interpretation company, today announced that it has been awarded a contract by the Johns Hopkins University School of Medicine. Under the agreement, Knome will supply its informatics services and software tools to Johns Hopkins’ landmark study to uncover genetic variants that contribute to asthma in African American and African Caribbean populations. The 1,000 genomes in the study will come from participants of African descent from 15 academic research centers across the United States, the Caribbean, and South America—as well as from four additional research sites in Western Africa.
In addition to annotating the genomes in the study, Knome’s informatics platform will transform each genome’s raw sequence information into a dataset suitable for comparative interpretation. Knome’s advanced software tools, including knomeVARIANTS and knomePATHWAYS, will then be used by Johns Hopkins researchers to shortlist candidate causal variants, genes, and gene networks.
“We are delighted to be working with Johns Hopkins,” said Martin Tolar, MD, PhD, Chief Executive Officer of Knome. “The Johns Hopkins team has always been on the cutting-edge of genomics. The fact that they have selected us for a project of this magnitude validates the superior quality of our whole genome informatics platform and interpretation tools.”
About Knome
Knome is a commercial stage life sciences company that specializes in the interpretation of human genomes. Knome supports researchers with the informatics and software tools they need to investigate the genetic basis of human disease and drug response. In addition, the company provides researchers, drug developers and clinics with end-to-end genome interpretation solutions.